Failure of conventional retrograde cystography to detect bladder ruptures in pelvic trauma
© The Author(s) 2010
Received: 27 February 2010
Accepted: 15 November 2010
Published: 8 December 2010
Conventional retrograde cystography is often used to investigate patients with suspected bladder ruptures in pelvic trauma. Clinical indicators suggestive of a rupture include haematuria and suprapubic tenderness and should increase the suspicion of bladder and urinary tract injury and prompt the clinician to undertake further investigations. Two patients with high-energy pelvic fractures had bladder ruptures detected intraoperatively despite normal preoperative retrograde cystogram. Both patients had significant clinical indicators suggestive of underlying bladder and urinary tract injury. In both cases, a routine conventional retrograde cystogram was performed but failed to identify the full extent of the bladder injury. A possible reason for misdiagnosis in these cases is the delay between injury and investigation due to tertiary referral of care.
KeywordsPelvic trauma Bladder rupture Cystography
Bladder injuries occur in up to 8% of cases with pelvic trauma . Many clinical indicators are suggestive and should prompt the clinician to undertake further investigations. Mortality rates range from 11% to 44% , but this is commonly attributed to the associated polytrauma . Conventional retrograde cystography has been considered the gold standard for investigating such patients [1, 4] and has a reported sensitivity of 100% [1, 3–6]. More recently, computed tomography (CT) cystography has been used as an adjunct to trauma CT to evaluate bladder trauma, showing similar accuracy rates . This procedure involves retrograde administration of contrast into the bladder through a catheter and performing a further scan in addition to the trauma CT. . We describe two cases in which conventional retrograde cystography failed to detect a bladder rupture in patients with an associated pelvic fracture. In both cases, informed consent was obtained for inclusion in this report. The purpose of this case report is to highlight such occurrences, the possible reason for failure and the implications occurring as a result.
After copious irrigation, the fractures were stabilised as previously planned, and the bladder was repaired by a urologist. Urethral and suprapubic catheters were left in situ. Follow-up urethrocystograms revealed no remaining leaks, and catheters were sequentially removed.
After initial trauma surveys, he was catheterised without difficulty and had haematuria. A urology review was undertaken and a decision made to manage conservatively. A contrast-enhanced CT scan did not identify kidney or bladder injury. The patient was transferred to a regional pelvic trauma unit for pelvic stabilisation 10 days after the initial injury. A routine preoperative urethrocystogram revealed a small bladder-neck tear. Urology input was sought to confirm this, and a urethral catheter was left in situ. A laparotomy was performed to create a defunctioning colostomy. On entering the peritoneal cavity, further intraperitoneal and extraperitoneal ruptures were seen in addition to the bladder-neck tear. Both injuries were repaired by urologists and a suprapubic catheter inserted. An external fixator was applied to stabilise the pelvis. A urethrocystogram 4 weeks after bladder repair revealed no further leaks, and catheters were sequentially removed.
Bladder ruptures can be categorised into extraperitoneal (60%), intraperitoneal (30%) and combined (10–12%) . Extraperitoneal ruptures are usually associated with pelvic fractures, most commonly occurring along the anterolateral aspect or bladder base. These injuries are due either to a shearing effect with disruption of the pelvis or direct bony penetration . Intraperitoneal ruptures result from severe blunt lower-abdominal or pelvic trauma to a distended bladder. This leads to sudden intravesical pressure increase and rupture, often creating horizontal tears at the dome being the weakest point. Lateral compression fractures and pubic symphysis diastasis injuries are more commonly associated with bladder injuries . Despite occurring relatively commonly, bladder injuries are still missed. In a recent study, 1% of cases were missed due to misinterpretation of cystogram images . The clinical indicators suggestive of bladder trauma include suprapubic pain or tenderness, inability to void and low urine output. Unfortunately, in the presence of a pelvic fracture, these signs are almost always present.
The investigation of choice in our institution for suspected bladder injuries is retrograde cystography. Increasingly, retrograde CT cystography is being used with similar accuracy rates [1, 3–6]. To prevent false negatives, the bladder should be adequately distended with at least 250–300ml of fluid; radiographs should be taken in at least two projections and include a postdrainage film to visualise extravasated contrast . No postdrainage films are needed for CT cystography.
In case 2 in this report, a correctly identified simple bladder-neck tear could have been treated with a urethral catheter alone. However, the cystogram failed to detect additional intraperitoneal and extraperitoneal ruptures, which represent more significant injuries requiring formal repair and a suprapubic catheter. One of the possible reasons the cystogram failed to detect the full extent of the leaks is the time span from injury to investigation—7 days in case 1 and 11 in case 2. The average time to surgery for pelvic/acetabular fractures in our unit is 10 days, comparing favourably with other units around the country. It is possible that the bladder injury had become walled off with fibrous adhesions to the overlying rectus and was disturbed by the surgical approach. Although a trauma CT scan failed to detect a bladder rupture at day 1, no formal cystogram was performed in either case, and perhaps that could have identified the injury sooner.
Failure to diagnose a bladder rupture prior to pelvic stabilisation surgery has a number of implications. Not all hospitals in which pelvic surgery is undertaken have a urologist available at all times to assist with bladder repair. From a surgical planning perspective, ideally, the patient should be made aware of the possibility of a suprapubic catheter prior to surgery and the possible associated increased risk of metal-work infection. A medicolegal implication also exists in that a negative preoperative retrograde cystogram does not absolutely imply that a rupture found intraoperatively, or even postoperatively, was caused by the surgeon during fracture repair. Patients and surgeons should be aware that even contrast imaging of the bladder may not detect all injuries.
Conflict of interest
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- Cass AS (1989) Diagnostic studies in bladder rupture. Urol Clin of North Am 16:267–273 (PMID:2652855)Google Scholar
- Rehm CG, Mure AJ, O’Malley KF, Ross SE (1991) Blunt traumatic bladder rupture: The role of retrograde cystogram. Ann Emerg Med 20:845–847. doi:10.1016/S0196-0644(05)81424-6PubMedView ArticleGoogle Scholar
- Carroll PR, McAninch JW (1984) Major bladder trauma: mechanisms of injury and a unified method of diagnosis and repair. J Urol 132:254–257 (PMID:6737572)PubMedGoogle Scholar
- Carroll PR, McAninch JW (1983) Major bladder trauma: the accuracy of cystography. J Urol 130:887–888 (PMID:6632094)PubMedGoogle Scholar
- Hsieh CH, Chen RJ, Fang JF, Lin BC, Hsu YP, Kao JL, Kao YC, Yu PC, Kang SC (2002) Diagnosis and management of bladder injury by trauma surgeons. Am J Surg 184:143–147 (PII:S0002-9610 (02) 00913-3)PubMedView ArticleGoogle Scholar
- Quagliano PV, Delair SM, Malhotra AK (2006) Diagnosis of blunt bladder injury: a prospective comparative study of computed tomography cystography and conventional retrograde cystography. J Trauma 61:410–421. doi:10.1097/01.ta.0000229940.36556.bfPubMedView ArticleGoogle Scholar
- Corriere JN Jr, Sandler CM (1986) Management of the ruptured bladder: seven years of experience with 111 cases. J Trauma 26:830–833. doi:10.1016/S0022-5347(01)67699-7PubMedView ArticleGoogle Scholar
- Ziran BH, Chamberlin E, Shuler FD, Shah M (2005) Delays and difficulties in the diagnosis of lower urologic injuries in the context of pelvic fractures. J Trauma 58:533–537. doi:10.1097/01.TA.0000152561.57646.80PubMedView ArticleGoogle Scholar
- Dunstan E, Bircher M (2000) Urological pitfalls in unstable pelvic fractures. Injury 31:379–382 (PII:S0020-1383 (99) 00290-9)PubMedView ArticleGoogle Scholar