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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 Demographics characteristics of the polytherapy per-treatment group and monotherapy per-treatment group

From: Polytherapy versus monotherapy in the treatment of tibial non-unions: a retrospective study

 

Polytherapy per-treatment (n = 20)

Monotherapy per-treatment (n = 24)

P value

Age (Mean ± SD) (years)

47.4 ± 14.0

52.5 ± 13.3

0.223

Female (%)

5 (25%)

7 (29%)

0.514

BMI (Mean ± SD) (weight (kg)/height (m)2)

25.0 ± 4.0

27.3 ± 5.7

0.135

NUSS (M (P25, P75))b

48 (43, 60)

38 (30, 50)

0.030 (z = −2.173)*

High-energy trauma cases (%)

11 (55%)

6 (25%)

0.063

Fracture type (0: I: II: IIIA: IIIB: IIIC)a

7:2:5:3:3:0

14:1:5:1:3:0

0.170 (z = −1.372)

Fixation (Intramedullary nail: Plate: conservative)c

8:7:5

8:13:3

0.878 (z = −0.153)

Isolated fracture (%)

16 (80%)

20 (83%)

1.000

Smoking status (%)

7 (35%)

4 (17%)

0.185

Hypertension (%)

0 (0%)

1 (4%)

1.000

Diabetes mellitus (%)

2 (10%)

1 (4%)

0.538

Hypercholesterolaemia (%)

1 (5%)

4 (17%)

0.356

Respiratory disease (%)

3 (15%)

6 (25%)

0.477

Congestive heart failure (%)

2 (10%)

3 (13%)

1.000

Coronary artery disease (%)

2 (10%)

2 (8%)

1.000

Prior cerebrovascular event (%)

0 (0%)

1 (4%)

1.000

Liver disease (%)

0 (0%)

0 (0%)

NAb

Cancer history in other systems (%)

2 (10%)

0 (0%)

0.201

Peripheral vascular disease (%)

1 (5%)

3 (13%)

0.614

  1. a Close fracture was recorded as ‘0’ in the present study. Gustilo open fracture classification: Type I: open fracture, clean wound, wound < 1 cm in length; Type II: open fracture, wound > 1 cm but < 10 cm in length without extensive soft-tissue damage, flaps, avulsions; Type IIIA: open fracture with adequate soft-tissue coverage of a fractured bone despite extensive soft-tissue laceration or flaps, or high-energy trauma (gunshot and farm injuries) regardless of the size of the wound; Type IIIB: open fracture with extensive soft-tissue loss and periosteal stripping and bone damage, usually associated with massive contamination, will often need further soft-tissue coverage procedure (i.e. free or rotational flap); Type IIIC: open fracture associated with an arterial injury requiring repair, irrespective of degree of soft-tissue injury. b In both the monotherapy patients group and the polytherapy patients group, there are no cases with liver disease. Therefore, the P value is not applicable (NA). * P < 0.05