Table 4 Adverse reactions and side effects to antimicrobials

Wachtel N (2023) [22]

Abdominal pain (n = 3)

Meteorism (n = 5)

Diarrhea (n = 3)

Nausea (n = 4)

Eczema (n = 2)

Abdominal pain (n = 1)

Meteorism (n = 2)

Diarrhea (n = 0)

Nausea (n = 4)

Eczema (n = 1)

To identify cases of adverse reactions and side effects to antimicrobials, patients were asked about the occurrence of signs or symptoms of intestinal disorders (meteorism, abdominal pain, nausea or vomiting, and diarrhea) and hypersensitivity reactions (eczema, pruritus, and anaphylactic shock) in the first 14 days after arthroscopy, which were classified by the patients as mild or severe. Patients who received preoperative antibiotics had significantly more adverse reactions and side effects related to the administration of these drugs than patients who did not receive antibiotic prophylaxis (16.2% versus 5.5%; p = 0.029, chi-squared test). Also, one out of ten patients who use antimicrobials has adverse reactions and side effects to these drugs