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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 4 Performance of IL-6 and PMN% in the diagnosis of PJI

From: Joint fluid interleukin-6 combined with the neutral polymorphonuclear leukocyte ratio (PMN%) as a diagnostic index for chronic periprosthesis infection after arthroplasty

Test

IL-6

PMN%

PMN% + IL-6

Sensitivity (%)

83.33%

96.67%

96.70%

Specificity (%)

83.33%

73.33%

93.33%

PPV (%)

83.33%

78.38%

93.55%

NPV (%)

83.33%

95.65%

96.55%

LR + 

5

3.625

14.50

LR −

0.2

0.045

0.04

DOR

25

80.56

406

  1. CRP C-reactive protein, ESR erythrocyte sedimentation rate, PJI periprosthetic joint infection, PPV positive predictive value, NPV negative predictive value, LRs likelihood ratio, DOR diagnostic odds ratio