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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 3 Sensitivity, specificity, PPV, NPV, and accuracy of inflammatory markers

From: Joint fluid interleukin-6 combined with the neutral polymorphonuclear leukocyte ratio (PMN%) as a diagnostic index for chronic periprosthesis infection after arthroplasty

Index

AUC (95% CI)

Cutoff value (pg/ml or %)

Sensitivity (95% CI) (%)

Specificity (95% CI) (%)

Accuracy (%)

IL-6

0.901 (0.827 to 0.975)

662.50

83.33 (64.55 to 93.69)

83.33 (64.55 to 93.69)

83.33

PMN%

0.914 (0.841 to 0.988)

51.09

96.67 (80.95 to 99.83)

73.33 (53.83 to 87.02)

85.00

PMN% + IL-6

0.983 (0.959 to 1.000)

/

96.67 (80.95 to 99.83)

93.33 (76.49 to 98.84)

95.00

  1. PPV positive predictive value, NPV negative predictive value, AUC area under the curve, CI confidence interval