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Official Journal of the Italian Society of Orthopaedics and Traumatology

Fig. 2 | Journal of Orthopaedics and Traumatology

Fig. 2

From: The value of sonication in the differential diagnosis of septic and aseptic femoral and tibial shaft nonunion in comparison to conventional tissue culture and histopathology: a prospective multicenter clinical study

Fig. 2

ROC curves for group discrimination based on CFU per ml sonication fluid (SF) determined by the membrane filtration method. A Discrimination of aseptic and septic nonunion; AUC = 0.77 (95% CI 0.67–0.87); optimal cut-off value that maximizes the Youden index (0.45) is ≥ 13.6 CFU/10 ml SF. B Discrimination of regular healed fractures and septic nonunion; AUC = 0.78 (95% CI 0.67–0.89); optimal cut-off value that maximizes the Youden index (0.47) is ≥ 0.6 CFU/10 ml SF

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