Fig. 2From: The value of sonication in the differential diagnosis of septic and aseptic femoral and tibial shaft nonunion in comparison to conventional tissue culture and histopathology: a prospective multicenter clinical studyROC curves for group discrimination based on CFU per ml sonication fluid (SF) determined by the membrane filtration method. A Discrimination of aseptic and septic nonunion; AUC = 0.77 (95% CI 0.67–0.87); optimal cut-off value that maximizes the Youden index (0.45) is ≥ 13.6 CFU/10 ml SF. B Discrimination of regular healed fractures and septic nonunion; AUC = 0.78 (95% CI 0.67–0.89); optimal cut-off value that maximizes the Youden index (0.47) is ≥ 0.6 CFU/10 ml SFBack to article page