Official Journal of the Italian Society of Orthopaedics and Traumatology
Table 1 Baseline characteristics of the included studies
Author, year | Country | Study design | Total population | Carpal tunnel syndrome, n (%) | HRT used in case, n (%) | HRT used in control, n (%) | Age (mean ± SD) | Duration of HRT used, year (median, IQR) | Type of HRT | Adjusted data |
|---|---|---|---|---|---|---|---|---|---|---|
Tang, 2022 [6] | Taiwan | Case–control | 118,309 | 4535 (3.8) | 2,334 (51.5) | 31,958 (28.1) | 51 | N/A | N/A | Yes |
Rousan, 2018 [7] | USA | Randomized-control trial | 16,053 | 841 (5.2) | 376 (44.7) | 7704 (50.6) | 65.9 ± 5.6 | – | – | No |
CEE trial | 6,833 | 465 (6.8) | 203 (43.6) | 3177 (49.8) | 65.7 ± 6 | 7.2 (6.4, 8.1) | CEE | No | ||
EP trial | 9,220 | 376 (4.1) | 173 (46) | 4527 (51.2) | 66.2 ± 5.4 | 5.6 (4.8, 6.5) | EP | Yes | ||
Ricco, 2016 [14] | Italy | Cross sectional | 631 | 48 (7.6) | 39 (81.2) | 264 (45.2) | 38.1 ± 7.8 | > 5 | N/A | Yes |
Geoghegan, 2004 [16] | UK | Case–control | 16,955 | 3391 (20) | 556 (16.4) | 1799 (13.3) | 46 ± 20 | N/A | N/A | Yes |
Ferry, 2000 [15] | England | Nested case–control | 2528 | 1264 (50) | 61 (4.8) | 47 (3.7) | 41.9 | N/A | N/A | No |
Solomon, 1999 [11] | USA | Case–control | 115,205 | 627 (16.7) | 5 (0.7) | 3 (0.8) | 73% over 64 years old | N/A | N/A | Yes |
Dieck, 1985 [13] | USA | Case–control | 1083 | 40 (3.8) | 21 (52.5) | 329 (31.5) | Range 45–74 years old | N/A | N/A | No |