Official Journal of the Italian Society of Orthopaedics and Traumatology
From: Which serum markers predict the success of reimplantation after periprosthetic joint infection?
Variable | CRP | ESR | D-Dimer | Fibrinogen |
---|---|---|---|---|
Area under the curve (95%CI) | 0.829 (0.668–0.990) | 0.795 (0.647–0.943) | 0.716 (0.573–0.859) | 0.831 (0.685–0.978) |
Optimum cutoff value | 9.4 mg/L | 29 mm/h | 1740 ng/mL | 365.6 mg/dL |
No. of patients | ||||
True negative | 100 | 95 | 73 | 84 |
False negative | 3 | 4 | 3 | 3 |
False positive | 8 | 13 | 28 | 17 |
True positive | 8 | 7 | 8 | 8 |
Sensitivity (%) | 72.7 (39.3–92.7) | 63.6 (31.6–87.6) | 72.7 (39.3–92.7) | 72.7 (39.3–92.7) |
Specificity (%) | 92.6 (85.5–96.5) | 88.0 (80.0–93.2) | 72.3 (62.3–80.5) | 83.2 (74.1–89.6) |
Positive predictive value (%) | 50.0 (25.5–74.5) | 35.0 (16.3–59.1) | 22.2 (10.7–39.6) | 32.0 (15.7–53.6) |
Negative predictive value (%) | 97.1 (91.1–99.2) | 96.0 (89.4–98.7) | 96.1 (88.1–99.0) | 96.6 (89.6–99.1) |