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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 6 Comparison of all tested biomarkers in the different PJI subgroups

From: C-reactive protein (CRP)/albumin-to-globulin ratio (AGR) is a valuable test for diagnosing periprosthetic joint infection: a single-center retrospective study

Biomarkers

Culture-positive PJI (N = 32)

Culture-negative PJI (N = 15)

P

Acute PJI (N = 10)

Chronic PJI (N = 37)

P

CRP (mg/L)

60.82 ± 96.38

23.08 ± 44.40

0.002*

70.08 ± 142.90

43.02 ± 62.49

0.459

ESR (mm/h)

48.94 ± 29.03

40.73 ± 32.24

0.373

45.00 ± 29.97

46.68 ± 30.40

0.845

NLR

4.95 ± 3.20

3.33 ± 2.16

0.035*

4.28 ± 4.23

4.47 ± 2.62

0.298

PLR

234.04 ± 111.87

192.69 ± 154.90

0.034*

172.75 ± 55.15

233.84 ± 137.90

0.363

PVR

34.99 ± 12.76

33.74 ± 13.04

0.741

34.03 ± 14.27

34.74 ± 12.48

0.755

GLB (g/L)

36.14 ± 7.15

36.59 ± 8.46

0.616

32.95 ± 6.48

37.18 ± 7.58

0.164

AGR

1.09 ± 0.33

1.14 ± 0.24

0.167

1.27 ± 0.36

1.06 ± 0.28

0.122

CRP/AGR

62.97 ± 97.94

26.26 ± 48.49

0.004*

68.77 ± 144.15

46.52 ± 65.23

0.311

  1. Values are given as mean ± SD
  2. CRP C-reactive protein, ESR erythrocyte sedimentation rate, NLR neutrophil-to-lymphocyte ratio, PLR platelet-to-lymphocyte ratio, PVR platelet-to-mean-platelet-volume ratio, GLB globulin, AGR albumin-to-globulin ratio
  3. *P < 0.05