Official Journal of the Italian Society of Orthopaedics and Traumatology
Table 4 Performance of different individual biomarkers for the diagnosis of PJI
Biomarker | AUC (95%CI) | Optimal cutoff | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|
CRP | 0.896 (0.838–0.938) | 6.59 mg/L | 82.98% | 83.76% | 67.24% | 92.45% |
ESR | 0.829 (0.763–0.883) | 34 mm/h | 63.83% | 95.73% | 85.72% | 86.82% |
NLR | 0.740 (0.666–0.805) | 2.71 | 68.09% | 70.09% | 47.77% | 84.54% |
PLR | 0.721 (0.646–0.788) | 132.67 | 85.11% | 51.28% | 41.24% | 89.55% |
PVR | 0.668 (0.590–0.739) | 34.31 | 46.81% | 83.76% | 53.66% | 79.68% |
GLB | 0.719 (0.644–0.787) | 33.8 g/L | 63.83% | 74.36% | 50.00% | 83.65% |
AGR | 0.767 (0.694–0.829) | 1.19 | 68.09% | 76.07% | 53.34% | 85.58% |
CRP/AGR | 0.902 (0.845–0.943) | 5.08 | 82.98% | 82.91% | 66.11% | 92.38% |