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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 Clinical outcomes of both groups

From: Tranexamic acid reduces blood loss in primary total hip arthroplasty performed using the direct anterior approach: a one-center retrospective observational study

Variable

TXA group (n = 39)

n (%) or mean ± SD (range)

Control group (n = 31)

n (%) or mean ± SD (range)

95% CI (lower to upper)

p-Value

TXA group

Control group

Operative time (min)

57.4 ± 12.8 (43–109)

60.4 ± 11.7 (42–89)

53.4–61.4

56.3–64.5

0.315

Intraoperative blood loss (mL)

106.5 ± 36.1 (78–200)

122.0 ± 32.6 (75–207)

95.5–117.5

111.0–133.0

0.067

Hidden blood loss (mL)

630.5 ± 98.6 (409–807)

893.4 ± 140.3 (644–1175)

599.5–661.5

844.4–942.4

< 0.001

Total blood loss (mL)

736.9 ± 102.2 (567–927)

1015.4 ± 152.4 (773–1285)

704.9–768.9

961.4–1069.4

< 0.001

HBpost-1* (g/L)

108.9 ± 14.9 (85–140)

99.2 ± 13.8 (80–132)

104.2–113.6

94.3–104.1

0.007

HBpost-3* (g/L)

87.4 ± 16.3 (63–128)

79.8 ± 10.9 (56–110)

82.3–92.5

76.0–83.6

0.029

Postoperative HB drop (g/L)

46.8 ± 10.8 (22–80)

55.0 ± 13.7 (31–79)

43.4–50.2

50.2–59.8

0.007

Transfusion rate (%)

2.6% (1/39)

12.9% (4/31)

  

0.279††

Postoperative LHS (day)

4.3 ± 0.8 (3–6)

4.6 ± 0.8(3–6)

4.1–4.6

4.3–4.9

0.124

DVT (%)

2.6% (1/39)

3.2% (1/31)

  

1.000††

Harris hip score (point)

91.8 ± 4.9 (80–100)

91.1 ± 6.1 (83–100)

90.3–93.3

89.0–93.2

0.596

  1. * Hpre = initial preoperative HB level, HBpost-1 = HB level of first postoperative day, HBpost-3 = HB level of third postoperative day, Postoperative HB drop = HBpre – HBpost-3
  2. Student’s t-test was used
  3. ††Chi-squared test was used