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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 Adjuvant chemotherapy pre- and postoperatively

From: Definitive surgery of primary lesion should be prioritized over preoperative chemotherapy to treat high-grade osteosarcoma in patients aged 41–65 years

Date (year)

Number of cases

Anticancer drug

Number of cases

1981–1983

4

ADM, CPA, VCR, MTX

ADM

ADM, CPA

2

1

1

1984–1991

4

ADM, CDDP

ADM, CDDP, BCD

ADM, CDDP, BCD, VCR.IFM.

CDDP, MTX

1

1

1

1

1992–2005

11

ADM, CDDP, IFM, BCD, MTX

ADM, CDDP, IFM, BCD

ADM, CDDP, IFM, MTX

CDDP, BCD, CBDCA

CDDP, IFM, MTX

CDDP, IFM, BCD

ADM, IFM, BCD

2

3

2

1

1

1

1

2006

8

ADM, CDDP

ADM, CBDCA

ADM, CDDP, CBDCA

ADM, CDDP, IFM

ADM, CDDP, CBDCA, VP-16

CDDP, CBDCA, VP-16

CBDCA

1

1

1

1

2

1

1

Total

27

 

27