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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 Factors involved in the placebo effect

From: Measuring the placebo effect in carpal tunnel syndrome

Patient and environment or psychosocial determinants of the placebo effect

Pathology involved

Measured item

Past effect of active treatments

Psychological mediators (expectations, desires, and emotions)

Brain structures involved in reward/aversion and regulation of emotions

Endogenous opioids

Classical conditioning

Physician

Cues that signal that an active treatment has been given

Empathy

Type of treatment

Type of administration

Look of the product