Fig. 2

Male 49-year-old patient with grade III open fracture of the right leg (a). The fracture was treated with EF and placement of a cement spacer into the bone defect. Soft tissues were reconstructed at 20 days from trauma with a free anterolateral thigh flap (b). At 5 months, we removed the spacer, and the defect was grafted with the mixed graft and the EF was replaced by a medial locking plate (c). At 2 years, there were no radiological nor macroscopic signs of integration of the graft (d, f). Last follow-up (e)