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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 Outcomes at 26 weeks

From: Clinical and radiographic comparison of a single LP-PRP injection, a single hyaluronic acid injection and daily NSAID administration with a 52-week follow-up: a randomized controlled trial

 

PRP

HA

NSAID

P

Patients

33

32

33

 

Responders [no. (%)]

 20% decrease WOMAC pain

16 (48)

7 (21)

5 (15)

< 0.001

 20% decrease WOMAC stiffness

15 (45)

5 (15)

4 (12)

< 0.002

 20% decrease WOMAC physical function

15 (45)

5 (15)

4 (12)

< 0.05

 20% decrease VAS

16 (48)

8 (25)

6 (18)

< 0.021

Change from baseline

 WOMAC pain

  % change from baseline

− 22.38

− 14.5

− 5.9

< 0.001

  End of follow-up

4.72 ± 0.87

5.15 ± 0.84

5.75 ± 0.43

< 0.005

 WOMAC stiffness

  % change from baseline

− 18.3

− 0.5

2.9

< 0.05

  End of follow-up

3.36 ± 0.5

3.56 ± 0.5

4.18 ± 0.39

< 0.001

 WOMAC physical function

  % change from baseline

− 21.1

− 12

0.6

< 0.001

  End of follow-up

± 0.6

28.62 ± 0.9

32.69 ± 0.8

< 0.001

 WOMAC total

  % change from baseline

− 21.06

− 12,39

− 0.06

< 0.03

  End of follow-up

33.6 ± 1.2

37.34 ± 1.2

42.63 ± 1.02

< 0.002

 VAS

  % change from baseline

− 20.2

− 13.92

− 5.4

< 0.001

  End of follow-up

4.9 ± 0.52

5.21 ± 0.6

5.81 ± 0.39

< 0.001

  1. A primary response was defined as the percentage of patients having a 20% decrease in the summed score for the WOMAC pain from baseline to week 26. Quantitative variables are expressed as mean standard deviation. P < 0.05 is considered statistically significant