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Journal of Orthopaedics and Traumatology

Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 3 Micro CT results at 4- and 8-week time-points

From: The effect of locally delivered recombinant human bone morphogenetic protein-2 with hydroxyapatite/tri-calcium phosphate on the biomechanical properties of bone in diabetes-related osteoporosis

Groups

Bone mineral density*

p value

Saline

 4 weeks

0.951 ± 0.0179

–

 8 weeks

1.01 ± 0.852

–

Buffer + HA/TCP

 4 weeks

1.43 ± 0.116

0.0001

 8 weeks

1.15 ± 0.301

0.72

Low-dose rhBMP-2 + HA/TCP

 4 weeks

1.50 ± 0.0101

0.007

 8 weeks

1.06 ± 0.0223

0.90

High-dose rhBMP-2 + HA/TCP

 4 weeks

1.59 ± 0.217

0.002

 8 weeks

1.37 ± 0.271

0.03

  1. * Values represent ratio of BMD on operative side to that on contralateral non-operative side (mean ± standard deviation)
  2. p values represent comparison to control group. Bold indicates statistical significance
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