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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 General health at 4- and 8-week time-points

From: The effect of locally delivered recombinant human bone morphogenetic protein-2 with hydroxyapatite/tri-calcium phosphate on the biomechanical properties of bone in diabetes-related osteoporosis

Groups

Blood glucose* (mg/dl)

Age at surgery (days)

Weight at surgery (g)

Weight at death (g)

Weight change (g)

Saline (n = 5)

 4 weeks

444 ± 40

182 ± 15

408 ± 36

404 ± 28

−4 ± 17

 8 weeks

421 ± 44

184 ± 11

369 ± 30

401 ± 30

33 ± 24

Buffer + HA/TCP (n = 6)

 4 weeks

493 ± 22

187 ± 12

398 ± 40

385 ± 45

−13 ± 43

 8 weeks

433 ± 14

175 ± 20

394 ± 33

404 ± 35

10 ± 16

Low-dose rhBMP-2 + HA/TCP (n = 5)

 4 weeks

478 ± 38

174 ± 10

401 ± 15

407 ± 18

6 ± 7

 8 weeks

440 ± 37

161 ± 8

383 ± 60

383 ± 60

2 ± 17

High-dose rhBMP-2+ HA/TCP (n = 6)

 4 weeks

474 ± 44

176 ± 13

404 ± 27

387 ± 32

−16 ± 22

 8 weeks

430 ± 27

177 ± 13

425 ± 23

416 ± 11

−8 ± 18

  1. The data represent average values ± standard deviation
  2. * Blood glucose data represents mean data from animals in each treatment group resulting from measurements taken from blood drawn two or three times per week from each animal from onset of T1DM up to death