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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 Effect of protocol implementation on route of vitamin K administration and outcomes

From: An evidence-based warfarin management protocol reduces surgical delay in hip fracture patients

Variable

Pre-protocol (n = 27)

Post-protocol (n = 40)

p value

Route of VK administration

 Intravenous

12 (44.4 %)

36 (90 %)

<0.001

 Oral

3 (11.1 %)

0 (0 %)

 None

12 (44.4 %)

4 (10 %)

Admission to VK administration time (h), median (IQR)

18 (8–24)

7.6 (4–13)

0.003

VK administration to operation time (h), median (IQR)

64 (24–75)

29.3 (17–37)

0.005

Operation to warfarin recommencement time (h), median (IQR)

68.0 (50–100)

73.8 (51–100)

0.90

Admission to operation time (h), median (IQR)

73 (46–105)

37.7 (28–45)

<0.001

Surgery within 48 h of presentation

8 (30 %)

32 (80 %)

<0.001

Hospital length of stay

21.2 (16–36)

19.2 (14–33)

0.77

  1. IQR interquartile range, VK vitamin K
  2. Chi-square test
  3. Mann–Whitney test