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Journal of Orthopaedics and Traumatology

Official Journal of the Italian Society of Orthopaedics and Traumatology

Fig. 3 | Journal of Orthopaedics and Traumatology

Fig. 3

From: Pravastatin suppresses matrix metalloproteinase expression and activity in human articular chondrocytes stimulated by interleukin-1β

Fig. 3

Bar graph illustrating the effect of pravastatin concentration (x) on MMP activity (y) by normal human chondrocytes after initial stimulation with IL-1β. Cells cultured in the presence of IL-1β only served as an experimental control. The MMP activity of culture supernatants was investigated by cleavage of a fluorescent MMP specific substrate. Data are presented as mean ± standard deviation. *p < 0.05

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