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Journal of Orthopaedics and Traumatology

Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 1 Articular cartilage matrix metalloproteinase-3 (MMP-3) expression and Osteoarthritis Research Society International (OARSI) histopathology scores in all groups

From: Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3

 

Group 1

Group 2

Group 3

MMP-3 expression (%)

42.5 ± 21.0 (5–80)

14.4 ± 19.8 (0–50)

3.6 ± 4.1 (0–10)

P = 0.001

P = 0.429

 

OARSI histopathology scores

9.4 ± 3.9 (4–16)

5.1 ± 3.6 (1–9)

–

P = 0.004

P < 0.001

 
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