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Journal of Orthopaedics and Traumatology

Official Journal of the Italian Society of Orthopaedics and Traumatology

Fig. 4 | Journal of Orthopaedics and Traumatology

Fig. 4

From: Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3

Fig. 4

a Micrographs from group 1 (ACLT) showing matrix discontinuity at the superficial zone, matrix vertical and branched fissures into mid zone [hematoxylin and eosin (H&E) ×10]. b Micrographs from group 2 (ACLT + simvastatin) showing only superficial fibrillation (H&E ×20). c Micrographs from group 3 (control knees) showing a intact surface and normal matrix architecture (H&E ×20)

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