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Journal of Orthopaedics and Traumatology

Official Journal of the Italian Society of Orthopaedics and Traumatology

Fig. 2 | Journal of Orthopaedics and Traumatology

Fig. 2

From: Mechanically induced experimental knee osteoarthritis benefits from anti-inflammatory and immunomodulatory properties of simvastatin via inhibition of matrix metalloproteinase-3

Fig. 2

a Micrographs from group 1 (anterior cruciate ligament transection) distal femoral articular cartilage chondrocytes showing a high percentage of matrix metalloproteinase-3 (MMP-3) staining (MMP-3, immunoperoxidase ×20). b Micrographs from group 2 (anterior cruciate ligament transection + simvastatin) showing low percentage of MMP-3 staining (MMP-3, immunoperoxidase ×40). c Micrographs from group 3 (control knees) showing no MMP-3 staining (MMP-3, immunoperoxidase ×40)

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