Italian intersociety consensus statement on antithrombotic prophylaxis in hip and knee replacement and in femoral neck fracture surgery

Journal of Orthopaedics and Traumatology

Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 3 Dosage and time of administration of Fondaparinux

Active principle	Brand name	Dosage and time of administration
Fondaparinux	ARIXTRA^®	2.5 mg at least 6 h after surgery, then 2.5 mg/day^a If creatinine clearance 20–50 ml/min 1.5 mg^b

^aIn agreement with the latest edition of the American College of Chest Physicians (ACCP) guidelines [1], initiation may be postponed up to 24 h after the end of the intervention [9], although this has not been included in the label as yet
^bAccording to the recent guidelines of the European Society of Anaesthesiology [10], FON is contraindicated if creatinine clearance < 30 ml/min