Official Journal of the Italian Society of Orthopaedics and Traumatology
Active principle | Brand name | Dosage and time of administration |
---|---|---|
Enoxaparin | Clexane® | 4,000 IU 12 h before surgery, then 4,000 IU/day |
Nadroparin | Fraxiparine® Seleparin® | 38 IU/kg 12 h before surgery and 12 h after, 38 IU/kg every 24 h during the 3 days following surgery, thereafter increasing the dose to 57 IU/kg/day |
Dalteparin | Fragmin® | 5,000 IU 8–12 h before surgery, then 5,000 IU/day. Alternatively 2 h, 500 IU 1–2 before surgerya and 2,500 IU 8–12 h after, thereafter either 5,000 IU/day or (only in hip surgery) 2,500 IU 4–8 h after surgery then 5,000 IU/day |
Bemiparin | Ivor® | 3,500 IU 6 h after surgery, then 3,500 IU/day. Alternatively 3,500 IU 2 h before surgerya, then 3,500 IU/day |
Parnaparin | Fluxum® | 0.4 ml (4,250 anti-Xa IU) 12 h before surgery, then 0.4 ml (4,250 anti-Xa IU)/day |
Reviparin | Clivarin® | 0.4 ml (4,200 anti-Xa IU) 12 h before surgery, then 0.4 ml (4,200 anti-Xa IU)/day |