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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 Key questions, selected studies and recommendations on use of allograft in arthroscopic anterior cruciate ligament reconstruction

From: Graft selection in arthroscopic anterior cruciate ligament reconstruction

Key questions

Studies

Recommendations

Is use of allograft effective in patients with anterior cruciate ligament injury (with or without meniscal lesions and/or grade I/II focal chondral lesions) and a shared indication to arthroscopic reconstruction?

407 identified, 3 selected, 2 rated, 2 included

Clinical practice

Use of autograft is recommended in anterior cruciate ligament reconstruction. Use of allograft shows, in fact, higher failure rate and slightly increased risk of infective complications

Is use of allograft safe in patients with anterior cruciate ligament injury (with or without meniscal lesions and/or grade I/II focal chondral lesions) and a shared indication to arthroscopic reconstruction?

48 identified, 3 selected, 2 rated, 2 included

Research

Randomized studies are recommended, comparing the best techniques concerning the two types of graft (autograft and allograft) and providing information on the contextual (organizational, structural, cultural) determinants of effectiveness for each intervention