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Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 2 Lane and Sandhu histopathological scoring system modified by Heiple et al. [28]

From: Xenogenic demineralized bone matrix and fresh autogenous cortical bone effects on experimental bone healing: radiological, histopathological and biomechanical evaluation

Union (proximal and distal evaluated separately)

No evidence of union

0

Fibrous union

1

Osteochondral union

2

Bone union

3

Complete organization of shaft

4

Cancellous bone

No osseous cellular activity

0

Early apposition of new bone

1

Active apposition of new bone

2

Reorganizing cancellous bone

3

Complete reorganization of cancellous bone

4

Cortical bone

Non

0

Early appearance

1

Formation under way

2

Mostly reorganized

2

Completely formed

10

Marrow

None is resected area

0

Beginning to appear

1

Present in more than half of the defect

2

Complete colonization by red marrow

3

Mature fatty marrow

4

Total points possible per category

Proximal union

4

Distal union

4

Cancellous bone

4

Cortex

4

Marrow

4

Maximum score

20