Quantification of surgical trauma: comparison of conventional and minimally invasive surgical techniques for pertrochanteric fracture surgery based on markers of inflammation (interleukins)

Journal of Orthopaedics and Traumatology

Official Journal of the Italian Society of Orthopaedics and Traumatology

Table 4 Levels of interleukins pre- and postoperatively

	Conventional (36 subjects)	MIO (32 subjects)	Average difference (95 % CI)	p Value
IL-6 preoperatively	39.57 ± 47.77	25.21 ± 29.73	14.37 (−5.19 to 33.92)	0.1472
IL-6 postoperatively	78.41 ± 67.04	39.02 ± 37.36	39.39 (12.65 to 66.13)	0.0045
IL-8 preoperatively	244.69 ± 476.18	248.57 ± 518.68	−3.88 (−337.20 to 329.48)	0.9813
IL-8 postoperatively	32.88 ± 7.40	73.91 ± 105.47	−41.04 (−87.70 to 5.63)	0.0829
IL-10 preoperatively	4.51 ± 3.19	2.89 ± 1.55	1.62 (0.38−2.86)	0.0110
IL-10 postoperatively	11.27 ± 19.74	8.90 ± 24.89	2.37 (−8.45 to 13.19)	0.6634
TNF-α preoperatively	30.56 ± 30.19	26.38 ± 19.19	4.18 (−8.39 to 16.76)	0.5092
TNF-α postoperatively	39.52 ± 55.13	23.44 ± 17.31	16.08 (−4.54 to 36.70)	0.1241

The table shows the levels of interleukins IL-6, IL-8, IL-10, and TNF-α before and after operation and the comparison between the two groups; values are expressed in pg/ml. IL-6 level shows no significant difference between the two groups in the preoperative phase, whereas it becomes significant in the postoperative period (Student t test)