Dislocation after total hip arthroplasty with 28 and 32-mm femoral head
© The Author(s) 2010
Received: 23 March 2010
Accepted: 12 May 2010
Published: 27 May 2010
Dislocation after primary total hip arthroplasty (THA) is a significant complication that occurs in 2–5% of patients. It has been postulated that increasing the femoral head diameter may reduce the risk of dislocation. The purpose of this paper is to report our experiences with a change from a 28 to a 32-mm femoral head.
Materials and methods
The retrospective cohort study includes 2572 primary THA performed with a 28 or 32 mm diameter femoral head in the period February 2002 to July 2009. All patients were operated with a posterolateral approach, and all except 18 were operated because of osteoarthritis. Cemented stems were used in 1991 cases and uncemented stems in 581 cases. Cemented cups were used in 2,230 cases and uncemented cups in 342 cases. The patients have been routinely followed for 1–8 years in the 28-mm femoral head group and from 0.5–7.5 years in the 32 femoral head group. We defined a dislocation as an event in which the hip required reduction by a physician.
Dislocation occurred in 49 hips with a 28-mm femoral head and in 4 hips with a 32-mm femoral head with an odds ratio of 6.06 (95% CI = 2.05–17.8) (P < 0.001). Otherwise, there were no significant associations between sex, age, diagnosis and type of prosthesis.
Multivariate analyses of patients operated at our hospital indicate a significant association between femoral head diameter and dislocation after THA. There were no significant associations between dislocation and sex, age, diagnosis, or type of prosthesis.
KeywordsDislocation Head size Hip arthroplasty Prosthesis
Dislocation of a primary total hip arthroplasty (THA) is a significant complication. In 1982 Woo and Morrey reviewed 10,500 primary THAs and identified an overall dislocation rate of 3.2% . Later studies have reported a rate of 2–5% [2, 3]. Some hips dislocate more than once, and patients with recurrent dislocation have reported a worse outcome than after uncomplicated THA [4, 5].
The risk factors that predispose to dislocation include patient-related, operative, and implant design variables . It has been postulated that an increased femoral head diameter may reduce the risk of dislocation as a result of reduced component–component or component–bone impingement and increased translation that is required for hip dislocation [7–9]. Despite these theoretical advantages, the use of larger femoral heads in THA has been limited as a result of concerns regarding increased production of polyethylene wear debris and osteolysis. This is based primarily on the study of Livermore et al.  in which wear of 385 cemented total hips with conventional polyethylene liners articulating with 22, 28, and 32-mm femoral heads was measured. They reported increased volumetric wear rates, total volumetric wear, and amount of osteolysis for 32-mm heads compared with 22 and 28-mm heads.
Highly cross-linked polyethylene (XLPE) is an alternative bearing surface that was developed to improve polyethylene wear resistance and reduce osteolysis. XLPE has been studied extensively in vitro [11, 12], and in a Boston hip simulator it was shown that the linear wear rate of electron beam XLPE was extremely low and independent of femoral head size for standard size femoral heads (22–32 mm) . Preliminary clinical studies of XLPE in small series of patients undergoing THA have confirmed these promising findings with a 45–99% reduction in wear compared with conventional polyethylene at 3–5 years [14–20]. Based on these results we have increased the size of the femoral head gradually from 28 to 32 mm in an effort to reduce the incidence of dislocation after THA. The purpose of this paper is to report our experiences with this change to a larger femoral head.
Materials and methods
The mean age at the time of the operation was 68 years (range, 24–93 years) in the cohort with a 28 mm diameter femoral head, and 69 years (range, 24–91 years) in the cohort with a 32 mm diameter femoral head. There were 1,047 women (1,182 hips) and 365 men (395 hips) in the 28 mm cohort and 691 women (739 hips) and 242 men (256 hips) in the 32 mm cohort. All patients were operated with a posterolateral approach, and all except 18 were operated for osteoarthritis of the hip, either primary (2,296 cases) or secondary (258 cases). They were operated with a cemented stem in 1991 cases and an uncemented stem in 581 cases, and with a cemented cup in 2,230 cases and an uncemented cup in 342 cases.
The patients have been routinely followed for 1–8 years in the 28 mm group and for 0.5–7.5 years in the 32 mm group, and we defined dislocation as an event in which the hip required reduction by a physician. During follow-up, five hips have been revised because of infection and eight because of mechanical failures. Altogether 126 patients have died of unrelated causes. These patients have been censored at time point of revision or death. Survival free of dislocation after arthroplasty was estimated by use of the Kaplan–Meier survival method. The Cox proportional hazards model was used in a multiple variable model to assess the risk of dislocation in association with femoral head diameter, with adjustment for sex, age, diagnosis, and type of prosthesis (SPSS, Chicago, IL, USA). An alpha level of 0.05 was set for significance.
Kaplan–Meier survival from dislocation for 28 and 32-mm femoral heads
In this study we evaluated the effect of femoral head diameter on the risk of dislocation. We found that the dislocation risk was significantly higher for the 28 mm diameter heads than for the 32 mm diameter heads, with a relative risk of 6. In the whole cohort there were no significant associations with sex, age, diagnosis, or type of prosthesis.
The major weakness of our study is that it was not randomized. The strength of our study include a large study group of patients with strict inclusion criteria, all with diagnosis of osteoarthritis, undergoing surgery in the same hospital by the same surgeons, with the same surgical technique.
Most reports on femoral head diameters and dislocation have used historical controls, and only a few clinical studies have demonstrated that an increased femoral head diameter may reduce the risk of dislocation [7, 21–24], and most clinical studies have not demonstrated this effect [25–28]. One main reason for these discrepancies may be that in most cases hip dislocation has a multifactorial etiology, and the effect of a single variable requires a larger study population with control of operative and implant design variables. We isolated the effect of femoral head diameter as the single variable. Our study confirms and expands on previously published evidence that the dislocation rate is reduced by use of larger heads. Kelley et al.  found the rate of dislocation to be higher with a 22-mm-diameter head than with a 28-mm head when a posterior operative approach was used. Hedlundh et al.  demonstrated a higher risk of recurrent dislocation, but not overall dislocation, for 2,875 hips treated with a Lubinus implant with a 32-mm head compared with 3,192 treated with a Charnley implant with a 22-mm head, but there was no difference in overall dislocation. Also Bystrom et al.  found that the rate of revisions because of dislocation was lower for 32-mm heads than for 28-mm heads. However, as only reoperation because of dislocation was used as the end point, and because many patients with a dislocation never have a reoperation, the relationship between head diameter and overall risk of dislocation could not be assessed by this study.
The literature suggests that more than half of all dislocations occur within the first three months after surgery and more than three quarters within one year , and one series demonstrated that 70% of dislocations after THA occurred within the first month after surgery . Our observations are in agreement with these reports, because 37 of 53 dislocations occurred within 100 days after THA.
In a previous study multivariate analysis showed a moderate effect in favor of a 32-mm head compared with a 28-mm head . The strongest effect was, however, the operative approach with a significantly higher risk of dislocation with the posterolateral approach than with the anterolateral and transtrochanteric approaches. Most series have reported that the dislocation rate after a posterior surgical approach to the hip is 2–3 times greater than that seen after an anterior approach [31–34]. At our clinic we have routinely used the posterolateral approach, and in the choice of changing operative or implant variable to reduce the risk of dislocation, we chose a larger femoral head because this was simpler. Also, the availability of bearing surfaces that have been predicted to have low wear rates even with larger head diameters led us to the use of 32 mm diameter femoral heads. This attitude was based on biomechanical and clinical studies that have suggested substantially reduced wear rates with XLPE compared with conventional polyethylene sterilized in an inert environment [14–17].
We could not find any difference in risk of dislocation between men and women. In one study dislocation was reported to occur 2.5 times as often in women as in men , but this was not verified in other studies [35–37]. Also it has been noted that patients’ age is not a risk factor for dislocation [1, 36], but Ekelund et al.  found a nearly twofold risk of dislocation among very old patients (above 80 years). In our series, there were no associations between dislocation and sex and age.
In conclusion, our analyses of patients operated at our hospital indicate a significant association between femoral head diameter and rate of dislocation after THA. Otherwise we could not find any significant associations between dislocation and sex, age, diagnosis, or type of prosthesis.
Conflict of interest
This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
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